There is an interest in identifying Anaphase Promoting-Complex/Cyclosome (APC/C) inhibitors that lead to sensitivity to microtubule poisons as a strategy for targeting cancer cells.Using budding yeast Saccharomyces cerevisiae, peptides derived from the Mitotic Arrest Deficient 2 (Mad2)-binding motif of Cell Division Cycle The Development of a Secur
A 53-year-old man, previously healthy, presented with a slow-progressive enlarging mass in the midfrontal area which had developed 14 years previously without headache.On physical examination, this nodular reddish mass (11 x 7 x 5 cm) was fluctuant to pressure and tethered to the underlying frontal bone (A).There was no neurological deficit and no
Bread is one of the oldest foods known throughout history and even though it is one of the principal types of staple around the world, it usually lacks enough nutrients, including protein and fiber.As such, fortification is one of the best solutions to overcome this problem.Thus, the objective this study was to examine the effect of three levels of
Farmers are often overlooked and undervalued as sources of innovation, but can be powerful drivers of ingenuity and development.We evaluate historical developments in the Australian subterranean clover seed-production industry as a case study of farmer-driven innovation.Subterranean clover seed machinery patents (75% of which were Social inequaliti